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Strain promoted azide alkyne cycloaddition
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(a) Strain-promoted azide–alkyne cycloaddition (SPAAC)

Strain-promoted azide–alkyne 1,3-dipolar cycloadditions (SPAAC) for

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Strain promoted cycloaddition of azides and cyclooctynes.jpg

... Strain-promoted azide–alkyne cycloaddition (SPAAC) · Figure 5. Michael additions can selectively link a thiol group from any.

Enzyme-mediated labeling with azidooctanoic acid and SPAAC.tif

Figure 1

Highly accelerated inverse electron-demand cycloaddition of electron-deficient azides with aliphatic cyclooctynes | Nature Communications

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Copper-free strain-promoted alkyne azide cycloaddition.

Scheme 1. Various options of azide-alkyne cycloaddition reactions

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Chemistry

Strain-promoted azide–alkyne 1,3-dipolar cycloadditions (SPAAC) for... | Download Scientific Diagram

Figure 4 Key Features of the CuI-Catalyzed Azide-Alkyne Cycloaddition Reaction.

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Elsevier Chemistry

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Fig. 2. Bioorthogonal chemistry: Staudinger Ligation, Cu-catalyzed.

Cu-catalyzed azide-alkyne cycloaddition reaction

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Triazole analogs of phthalate plasticizers prepared by copper-free azide- alkyne click reaction

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Expanding and exploring the bioconjugation toolbox

Review articles on copper-free cycloaddition reactions:

A high-throughput-compatible assay to measure the degradation of endogenous Huntingtin proteins | Acta Pharmacologica Sinica

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Huisgen's 1,3-dipolar cycloaddition of azides and alkynes to.

Super Shiny Version of a Strain-Promoted Alkyne Azide Cycloaddition

(Figure 1) . Schematic representation of a SPAAC ligation reaction. The strain promoted alkyne-azide cycloaddition ...

(a) Schematic representation of the formation of HA-PEG hydrogels through a strain-promoted alkyne-azide cycloaddition reaction. (b) Photograph of a HA-PEG ...

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Bioorthogonal click reactions: copper(I)-catalysed azide-alkyne cycloaddition (CuAAC

[Named Reaction #3]: 'Click' Chemistry : chemistry

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www.frontiersin.org

2018

Zoom. ODIBO-EG4-NHS for strain-promoted alkyne-azide cycloaddition ...

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Abstract

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NuLink Ph Azide | 10-Angstrom Spacer | SKU NCAZ03 | 3 mg, 3 x 1 mg Click to Buy

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Clockwise from top right: copper-catalyzed azide–alkyne ligation, strain-promoted azide–alkyne ligation, Staudinger ligation with a phosphino thioester, ...

Elsevier Chemistry

... cyclic polyesters based on the combination of ring opening polymerization (ROP) and self-accelerating double strain-promoted azide-alkyne cycloaddition ...

SPAAC between an azide and a difluorocyclooctyne eliminates the need for a copper catalyst and allows material fabrication under physiological conditions.

Strain-Promoted Azide-Alkyne Cycloaddition with Ruthenium(II)-Azido Complexes

S1 Fig. 1H NMR spectrum of 1-(3,4-Dihydroxy-5-iodomethyl-tetrahydrofuran-2-yl)-5-methyl-1H-pyrimidin-2,4-dione 3a (DMSO).

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Strain-promoted [3+2] Cycloaddition

NuLink Alkyl Azide | 11-Angstrom Spacer | SKU NCAZ01 | 3 mg, 3 x 1 mg | CuAAC Kitset Click to Buy

The reactivity will also increase with increasing ring strain, as is the case for dibenzo-fused cyclooctynes (DiBO and DiBAC) and bicyclo[6.1.0]non-4-yne ...

DBCO-S-S-NHS ester: sc-397266.

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Open AccessArticle

Strain Promoted Click Chemistry of 8-Azidopurine and 5-Azidopyrimidine Nucleosides and Nucleotides with Cyclooctynes and Applications to Living Cell Imaging

For instance, Ting et al. introduced an azido functionality onto specific proteins on the cell surface using a ligase enzyme. The azide-tagged protein is ...

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Figure 6. Native chemical ligation (NCL): this reaction proceeds.

... the use of metabolically labeled azido sugars and highly reactive cyclooctyne probes, through strain-promoted alkyne azide cycloadditions (SPAAC), ...

Application of nitrile oxide in the synthesis of miyakolide.tif

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One prominent example of click-chemistry is the reaction of Alkynes with Azide groups.

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Strain Promoted Huisgen Cyclization of Azides

Efficient Synthesis of DNA Conjugates by Strain-Promoted Azide–Cyclooctyne Cycloaddition in the Solid Phase

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Schematic representation of the BCN–azide frontier molecular orbital interactions emerging from our quantitative Kohn–Sham electronic-structure analyses.

Figure 4. Western blot protein visualization and identification after chronic ANL incorporation into neuronal protein and bio-orthogonal non-canonical amino ...

1,3-Dipolar cycloaddition

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Figure 12 I- Regioselective alkylation reaction with a 4.5-dibromo-1,2,3-triazole; II-Examples of the transformtion of the N2-Alkyl-4,5-dibromo-1,2 ...

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Copper-catalyzed alkyne-azidecycloaddition Mechanism ...

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2015

... alkyne-azide cycloaddition Cu-free. 6 Selection ...

Bioorthogonal Ligation Chemistry

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